Flow cytometry cell sorting and T-cell cytotoxicity assay laboratory

CLINICAL APPLICATION & CRITERIA

Immunotherapy & Checkpoint Inhibitors in China

Immunotherapy harnesses the body’s own immune system to recognize and destroy cancer cells. The most widely used class is immune checkpoint inhibitors — antibodies targeting PD-1, PD-L1, or CTLA-4 — that release natural brakes on T cells, enabling them to attack tumors. Unlike chemotherapy or targeted therapy, immunotherapy can produce durable, long-term remissions that persist years after treatment ends, even in advanced metastatic disease. Responses are enriched in patients whose tumors express predictive biomarkers such as PD-L1, high tumor mutational burden (TMB-H), or microsatellite instability (MSI-H/dMMR). Combination approaches with chemotherapy, targeted agents, or radiation continue to expand the受益 patient population.

CLINICAL CANCER INDICATIONS

Key Cancers Treated with Immunotherapy in China

World-leading first-in-class bispecific antibodies, high-affinity PD-1/PD-L1 inhibitors, and synergistic combination protocols across solid tumors:

Lung Cancer

First-in-class PD-1/VEGF bispecifics (Ivonescimab) and validated PD-1 antibodies achieving superior PFS in advanced EGFR-mutant and wild-type NSCLC.

Stomach & Colorectal Cancer

Approved first-line PD-1/CTLA-4 bispecifics (Cadonilimab) and chemo-immunotherapy regimens for esophageal, gastric, and MSI-H colorectal cancer.

Liver Cancer

Standard-of-care PD-1 plus anti-angiogenic combinations (Camrelizumab+Rivoceranib, Sintilimab+Bevacizumab) extending median overall survival.

WHY CHOOSE US

Why Choose China Cancer Help for Immunotherapy

A specialized cross-border continuum connecting international patients directly with China’s world-leading immuno-oncology ecosystem.

China has become a global powerhouse in immuno-oncology, with the world’s largest number of clinical trials for PD-1/PD-L1 inhibitors. Multiple domestically developed checkpoint antibodies — sintilimab (Innovent), tislelizumab (BeiGene), camrelizumab (Hengrui), toripalimab (Junshi), and penpulimab — have received NMPA approval, with several now recognized by the FDA and EMA. NRDL negotiations have driven anti-PD-1 prices down to roughly 10–20% of US list prices, making immunotherapy widely accessible to both domestic and international patients.

Chinese companies are pioneering novel bispecific antibodies — including ivonescimab, the world’s first approved PD-1×VEGF bispecific — which demonstrated a statistically significant overall survival benefit over standard PD-1 plus chemotherapy in squamous NSCLC, a result unmatched by any other anti-PD-(L)1 regimen. Fast-track NMPA approvals, a vast patient base for rapid clinical development, and extensive real-world data on high-incidence Chinese cancers (esophageal, gastric, liver, nasopharyngeal) make China a global leader in delivering cutting-edge immunotherapy.

CASE EVALUATION PATHWAY

A Structured Pathway from Records to Care

A transparent, four-stage continuum connecting preliminary clinical evaluation to official hospital acceptance, specialized inpatient care, and ongoing continuity.

01. Submit Records Online

Upload existing pathology reports, biomarker NGS profiles, and imaging scans through our secure clinical intake portal.

02. Pre-Screen & Doctor Match

Clinical eligibility and contraindication screening, matching your specific case with China's foremost oncology chiefs.

03. Doctor Consultation

One-on-one remote video consultation or written multidisciplinary assessment to confirm treatment protocol before travel.

04. Travel to China & Care

Expedited medical visa support, priority hospital admission, dedicated bilingual bedside escorts, and continuum follow-up.

PATIENT FAQS

Frequently Asked Questions

Key clinical, financial, and logistical insights for international Immune Checkpoint Inhibitors (ICI) patients considering care in China.

China has approved over 10 distinct domestic PD-1/PD-L1 antibodies and developed world-first bispecifics such as Cadonilimab (PD-1/CTLA-4) and Ivonescimab (PD-1/VEGF), demonstrating superior progression-free survival in Phase III head-to-head trials against global standards.
Standard evaluation includes PD-L1 expression (TPS and CPS scores by validated IHC), Microsatellite Instability (MSI-H/dMMR), and Tumor Mutational Burden (TMB-H). However, novel combination regimens frequently achieve responses even in PD-L1 negative tumors.
Leading Chinese cancer centers maintain standardized multidisciplinary irAE task forces. Patients undergo regular liver, thyroid, endocrine, and pulmonary monitoring, with immediate access to immunosuppressive protocols if necessary.
Immunotherapy is typically administered intravenously once every 2 to 3 weeks. Durable responses are typically maintained for 1 to 2 years, provided tolerance is maintained.

IMMUNOTHERAPY PRE-ASSESSMENT

Request a Confidential Case Review for Immunotherapy & Checkpoint Inhibitors

Submit your contact details, confirmed diagnosis, and main question below. You do not need to upload any medical files at this stage. Our clinical coordinator will contact you directly within 24–48 hours to discuss potential immunotherapy and checkpoint inhibitor pathways in China and assist you in gathering the specific medical records needed for expert hospital review.

    Immunotherapy & Checkpoint Inhibitors