OUR MEDICAL SPECIALISTS  >  GUANGDONG LUNG CANCER INSTITUTE (GLCI)

Prof. Wu Yilong, MD, PhD

Founder of Guangdong Lung Cancer Institute · Past President of CSCO · IASLC Cullen Awardee  |  Guangdong Provincial People's Hospital (GDPH)

Prof. Wu Yilong, MD, PhD
FOUNDER OF GUANGDONG LUNG CANCER INSTITUTE · PAST PRESIDENT OF CSCO · IASLC CULLEN AWARDEE

Prof. Wu Yilong, MD, PhD

Guangdong Lung Cancer Institute (GLCI)
Guangdong Provincial People's Hospital (GDPH)
  • Hospital Affiliation
    Guangdong Provincial People's Hospital (GDPH)
  • Clinical Specialty
    Thoracic Medical Oncology, Targeted Therapy & EGFR Resistance
  • Clinical Languages
    English, Mandarin, Cantonese
  • Clinical Experience
    40+ Years
  • Consultation Turnaround
    24–48 Hours Priority Review
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ACCREDITED CHAIR PROFILE & CLINICAL OVERVIEW

World Luminary in Targeted Therapy and Molecular Resistance in Lung Cancer

Prof. Wu Yilong, MD, PhD, is Tenured Director of the Guangdong Lung Cancer Institute (GLCI) at Guangdong Provincial People's Hospital, Past President of the Chinese Society of Clinical Oncology (CSCO), and Founder of the Chinese Thoracic Oncology Group (CTONG). Globally recognized as a titan in thoracic oncology, he received the prestigious Joseph W. Cullen Prevention/Early Detection Award from the International Association for the Study of Lung Cancer (IASLC).

Prof. Wu's seminal research fundamentally reshaped how non-small cell lung cancer (NSCLC) is diagnosed and treated worldwide. As principal investigator of pivotal global trials—including AURA3, ADAURA, FLAURA, and CTONG-1104—he proved the curative potential of adjuvant osimertinib in resected EGFR-mutated NSCLC and established targeted therapies as the unquestioned first-line standard of care.

Leading Asia's foremost precision oncology laboratory, Prof. Wu specializes in resolving complex molecular resistance pathways (e.g. EGFR T790M, C797S, MET amplification, HER2 mutations, and RET/ROS1 fusions). His clinic provides international patients access to cutting-edge antibody-drug conjugates (ADCs), bispecific antibodies, and customized combination protocols that sustain long-term survival in advanced disease.

Primary Appointment Director, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital
Global Distinctions IASLC Joseph W. Cullen Awardee; Highly Cited Researcher (Clarivate Global Top 1%)
National Governance Founder & Past President, Chinese Society of Clinical Oncology (CSCO); Chair, CTONG
International Guidelines Steering Committee Member, World Conference on Lung Cancer (WCLC); Fellow, ASCO / ESMO
CORE OPERATIVE MASTERY & CLINICAL EXCELLENCE

Procedural Frontiers & Department Innovations

Landmark ADAURA Adjuvant Targeted Protocol

Led the global phase III trial demonstrating an 80% reduction in disease recurrence with adjuvant osimertinib in stage IB-IIIA EGFR-mutated NSCLC.

Overcoming Complex EGFR Resistance

World leader in managing post-3rd generation TKI resistance through MET inhibitor combinations, HER3 ADCs, and customized dual-targeted regimens.

Perioperative Neoadjuvant Immunotherapy

Pioneered chemo-immunotherapy induction before surgery, raising major pathologic response (MPR) rates to >60% in resectable stage II/III lung cancer.

Circulating Tumor DNA (ctDNA) Dynamics

Translating ultra-deep liquid biopsy tracking into clinical decisions: identifying molecular relapse months before radiologic progression.

ACADEMIC AWARDS & LANDMARK TREATISES

Distinguished National & International Recognition

N ENGL J MED
Osimertinib in Resected EGFR-Mutated Non-Small-Cell Lung Cancer (ADAURA)
Historic practice-changing phase III trial establishing global standard in adjuvant targeted therapy.
THE LANCET
Gefitinib vs Vinorelbine+Cisplatin as Adjuvant Therapy in NSCLC
First prospective trial in medical history confirming targeted adjuvant superiority over chemotherapy.
LANCET ONCOLOGY
Overcoming Osimertinib Resistance in Advanced NSCLC
Landmark trial establishing MET combination paradigms for targeted resistance.
IASLC HONOR
IASLC Joseph W. Cullen Prevention & Scientific Distinction Award
Conferred by the International Association for the Study of Lung Cancer for lifetime contributions.

CASE INTAKE & TARGETED THERAPY TRIAGE

Request a Thoracic Oncology Review with Prof. Wu Yilong, MD, PhD

Submit recent next-generation sequencing (NGS) molecular panels, lung biopsy histopathology reports, contrast chest CT & brain MRI DICOM scans, and a chronological history of prior targeted/immunotherapy drugs for direct triage by Prof. Wu Yilong. Our medical team responds within 24–48 hours.

    Prof. Wu Yilong, MD, PhD