Next-generation sequencing and molecular pathology genetics laboratory

CLINICAL APPLICATION & CRITERIA

Targeted Therapy in China

Targeted therapy uses drugs designed to interfere with specific molecular drivers of cancer growth — mutated proteins, overexpressed receptors, or activated signaling pathways — rather than attacking all rapidly dividing cells. Classes include small-molecule tyrosine kinase inhibitors (TKIs), monoclonal antibodies, antibody-drug conjugates (ADCs), and PARP inhibitors. Treatment requires biomarker testing to identify actionable alterations such as EGFR, ALK, HER2, BRAF, BRCA, or NTRK, enabling a precision medicine approach that often achieves superior responses with fewer systemic side effects than conventional chemotherapy. Resistance is managed through sequential therapy and rational drug combinations.

CLINICAL INDICATIONS

Key Cancers Treated with Targeted Therapy

Precision biomarker-driven kinase inhibitors, next-generation ADCs, and multi-target agents matching individual tumor genomic alterations:

Lung Cancer

Access to 3rd/4th generation EGFR TKIs, brain-penetrant ALK/ROS1 inhibitors, and novel KRAS G12C/G12D small molecules ahead of Western commercial availability.

Breast Cancer

Innovative HER2-directed ADCs, CDK4/6 inhibitors, and PARP inhibitors for BRCA-mutant and HR-positive/HER2-low advanced breast cancers.

Stomach & Colorectal Cancer

NMPA-approved VEGFR inhibitors (Fruquintinib), HER2 ADCs, and Claudin 18.2 targeted therapies for refractory colorectal and gastric cancers.

WHY CHOOSE US

Why Choose China for Targeted Therapy

A specialized cross-border continuum providing international patients with direct access to China's leading targeted oncology pipeline.

China is a global leader in targeted therapy, driven by the uniquely high prevalence of EGFR mutations (40–50% of NSCLC) and other actionable biomarkers in its patient population. Domestic biopharmaceutical companies — Innovent, BeiGene, Hengrui, Chipscreen, and others — have developed multiple world-class targeted drugs, including furmonertinib (third-generation EGFR TKI), zanubrutinib (BTK inhibitor, FDA-approved), and surufatinib, with several reaching global markets through FDA and EMA approvals.

National volume-based procurement and NRDL negotiations have dramatically cut prices: osimertinib, gefitinib, and other once-expensive TKIs are now available at a fraction of Western list prices. The NMPA’s fast-track approval pathways mean novel agents reach Chinese patients rapidly, sometimes before US or European approval. With Grade 3A centers offering NGS molecular diagnostics, MDT molecular tumor boards, and bilingual international patient services, China provides some of the most accessible and advanced targeted oncology care in the world.

HOW IT WORKS

4 Steps to Treatment in China

A simple, step-by-step process from initial record review to your arrival and treatment in China.

01. Submit Records Online

Upload existing pathology reports, biomarker NGS profiles, and imaging scans through our secure clinical intake portal.

02. Pre-Screen & Doctor Match

Clinical eligibility and contraindication screening, matching your specific case with China's foremost oncology chiefs.

03. Doctor Consultation

One-on-one remote video consultation or written multidisciplinary assessment to confirm treatment protocol before travel.

04. Travel to China & Care

Expedited medical visa support, priority hospital admission, dedicated bilingual bedside escorts, and continuum follow-up.

PATIENT FAQS

Frequently Asked Questions

Key clinical, financial, and logistical insights for international patients considering care in China.
China has approved dozens of innovative domestically developed targeted drugs—including third-generation EGFR inhibitors (almonertinib, aumolertinib), selective VEGFR inhibitors (fruquintinib), and novel ADCs—available at substantial price advantages compared to Western markets.
Next-Generation Sequencing (NGS) of tumor tissue and circulating tumor DNA (ctDNA liquid biopsy) is conducted across 500+ cancer-related genes to identify actionable mutations, fusions, amplifications, and resistance pathways.
Yes. For approved oral targeted medications, hospital pharmacies can dispense prescribed treatment courses with official documentation, accompanied by structured remote oncology monitoring and repeat molecular monitoring.
When disease progression occurs, re-biopsy or liquid biopsy ctDNA testing is immediately performed to identify secondary resistance mechanisms (e.g. C797S, MET amplification) and switch to rational combination or next-line targeted protocols.

CONFIDENTIAL CASE EVALUATION

Start with a Confidential Clinical Case Review

Submit your basic case details below for an initial eligibility review. Our medical team coordinates directly with chief oncologists at top Chinese cancer centers, returning a preliminary assessment and roadmap within 24–48 hours.

✓ Free initial triage  •  ✓ Direct specialist coordination  •  ✓ 100% Confidential

    Molecular Targeted Therapy